Preventing mother-to-child transmission of HIV-1 requires a series of steps in the care of women and their infants during pregnancy, delivery, and the postpartum period. This review outlines the steps and summarizes progress in resource-limited countries and elsewhere.
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Issue Briefs
Accelerating Progress to Ending Pediatric HIV
Published March 2026
We are at a critical inflection point for children affected by HIV. In 2024 alone, 120,000 children were newly infected, and, without timely treatment, half of HIV positive infants will not reach their second birthday. Children remain left behind—a child with HIV is 6 times more likely to die than an adult without timely diagnosis. […]
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Topics:
HIV,
Pediatric HIV
Countries:
Global
Resource
Protecting Lives, Sustaining Progress
Published March 2026
The following landscape analysis of maternal and child health, HIV prevention, diagnosis, and treatment, and the historic strength of U.S. leadership in global aid provides an overview of these key areas of global health and recommendations for U.S. Congressional engagement and prioritization.
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Topics:
Advocacy,
Children,
Global Health Security,
Health System Strengthening,
HIV,
Maternal and Child Health,
Mothers and Infants,
Women
Journal Articles
An integrated, multidisciplinary management team intervention to improve patient‑centeredness, HIV, and maternal‑child outcomes in Lesotho
Published December 2024
Background Reducing perinatal HIV transmission and optimizing maternal and child health (MCH) outcomes in high HIV prevalence settings is an urgent, but complex, priority. Extant interventions over-emphasize individual-level provider and patient behaviors, and neglect critical health systems-level changes. The ‘Integrated Management Team to Improve Maternal-Child Outcomes (IMPROVE)’ study implemented a three-part, patient-centered, health-systems- level intervention […]
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Topics:
Maternal and Child Health
Countries:
Lesotho