Integrating Pediatric TB Services into Child Healthcare Services
A Cluster-randomized Stepped Wedge Trial (The INPUT Study)
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Overview
Country:
Cameroon; Kenya
Subject Matter:
Tuberculosis
This Unitaid-funded study used cluster randomization and a stepped wedge design to compare two strategies for case detection and management of TB in children under 5 years of age in Cameroon and Kenya. The included strategies were the current standard of care for pediatric TB services and the Unitaid CaP TB intervention that integrated pediatric TB services into key child healthcare services.
Data Collection Period: May 2019 – December 2021
- Findings published in BMC Public Health, May 2020: “Integrating pediatric TB services into child healthcare services in Africa: study protocol for the INPUT cluster-randomized stepped wedge trial“
- Findings presented at the 51st Union World Conference on Lung Health, October 2020: “Key clinical features among children under five with a presumptive diagnosis of TB and confirmed TB diagnosis in Sub-Saharan Africa”
- Findings presented at the 51st Union World Conference on Lung Health, October 2020: “Low-level care facilities as entry points for pediatric TB screening and case finding: a stepped-wedge randomized controlled study”
- Findings presented at the 12th International Workshop on HIV & Pediatrics, November 2020: “High HIV infection rates among children under five years of age identified as TB presumptive in sub-Saharan Africa“
- Findings presented at the 52nd Union World Conference on Lung Health, October 2021: “Integrating paediatric TB case detection at paediatric entry points in sub-Saharan Africa: results of the INPUT stepped-wedge cluster-randomised study”
- Findings presented at the 52nd Union World Conference on Lung Health, October 2021: “Prevalence and characteristics of TB among young children living with and those without HIV in sub-Saharan Africa”
