Prevention of Mother-to-Child Transmission

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The Association between HIV Status and Antenatal Care Attendance among Pregnant Women in Rural Hospitals in Lesotho

Journal Articles

Early and frequent antenatal clinic (ANC) attendance is important for promotion of healthy outcomes for mother and child. This study explored the relationship between HIV status at the first ANC visit and subsequent ANC attendance among pregnant women in Lesotho.

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Zimbabwe Program 2014 Annual Report

This report highlights Zimbabwe's work in-country to scale up prevention of mother-to-child HIV transmission and increase access to HIV care and treatment through innovation in 2014.

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Cote d'Ivoire Annual Report 2014

Technical Briefs

This report describes work accomplished under two CDC awards throughout 2014, Project Djidja and Project Keneya, which both strive to ensure access to prevention of mother-to-child transmission of HIV and HIV care and treatment services, while promoting local ownership and sustainability of this work in Cote d'Ivoire.

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Challenges in the Elimination of Pediatric HIV-1 Infection

Journal Articles

By Katherine Luzuriaga, M.D., and Lynne M. Mofenson, M.D.

Preventing mother-to-child transmission of HIV-1 requires a series of steps in the care of women and their infants during pregnancy, delivery, and the postpartum period. This review outlines the steps and summarizes progress in resource-limited countries and elsewhere.

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Evaluating the effectiveness of selected community-level interventions on key maternal, child health, and prevention of mother-to-child transmission of HIV outcomes in three countries (the ACCLAIM Project): a study protocol for a randomized controlled trial

Journal Articles

Efforts to scale up and improve programs for prevention of mother-to-child transmission of HIV (PMTCT) have focused primarily at the health facility level, and limited attention has been paid to defining an effective set of community interventions to improve demand and uptake of services and retention. Many barriers to PMTCT are also barriers to pregnancy, childbirth, and postnatal care faced by mothers regardless of HIV status. Demand for maternal and child health (MCH) and PMTCT services can be limited by critical social, cultural, and structural barriers. Yet, rigorous evaluation has shown limited evidence of effectiveness of multilevel community-wide interventions aimed at improving MCH and HIV outcomes for pregnant women living with HIV. We propose to assess the effect of a package of multilevel community interventions: a social learning and action component, community dialogues, and peer-led discussion groups, on the demand for, uptake of, and retention of HIV positive pregnant/postpartum women in MCH/PMTCT services.

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Pregnant and Postpartum Women’s Experiences and Perspectives on the Acceptability and Feasibility of Copackaged Medicine for Antenatal Care and PMTCT in Lesotho

Journal Articles

By Gill, Hoffman,Tiam, Mohai, Mokone, Isavwa, Mohale, Makhohlisa, Ankrah, Luo, Guay

To improve PMTCT and antenatal care-related service delivery, a pack with centrally prepackaged medicine was rolled out to all pregnant women in Lesotho in 2011. This study assessed acceptability and feasibility of this copackaging mechanism for drug delivery among pregnant and postpartum women.

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Lesotho's Minimum PMTCT Package: lessons learned for combating vertical HIV transmission using co-packaged medicines

Journal Articles

By Lotus McDougal, Mpolai M Moteetee, Florence Mohai, Malisebo Mphale, Binod Mahanty, Blandinah Motaung, Victor Ankrah

This article features our analysis of a program to improve prevention of mother-to-child HIV transmission (PMTCT) adherence by implementing a package given to all pregnant women (some including only prenatal vitamins and other information - some including both prenatal and PMTCT drugs for women who tested HIV-positive during pregnancy). This program was rolled out in Lesotho. Our study examines feasibility of the package.

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Accelerating the Elimination of Pediatric HIV and AIDS in Zimbabwe

Technical Reports

This report illustrates EGPAF’s work over five years (2010 - 2015) in Zimbabwe under CIFF funding. Through this award, EGPAF was able to scale up a variety of programmatic best practices, including community approaches, point-of-care HIV diagnosis technology and integrated and comprehensive health services throughout the country to ensure a total reduction in mother-to-child HIV transmission from 30% to 6%.

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