Maternal and Child Health

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Benefits and Risks of Antiretroviral Therapy for Perinatal HIV Prevention

Journal Articles

Randomized-trial data on the risks and benefits of antiretroviral therapy (ART) as compared with zidovudine and single-dose nevirapine to prevent transmission of the human immunodeficiency virus (HIV) in HIV-infected pregnant women with high CD4 counts are lacking.

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TIMIZA90 Project Factsheet

Fact Sheets

Timiza90 is a five-year (Oct 2016 to Sept 2021) U.S. Centres for Disease Control and Prevention (CDC)-funded Project which aims to support the implementation and expansion of high quality, sustainable, and comprehensive HIV prevention, care, and treatment programs.

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BRIDGING RURAL SUB-SAHARAN AFRICAN COMMUNITIES AND THE GLOBAL RESPONSE TO THE HIV AND AIDS EPIDEMIC

Issue Briefs

Lessons from the Advancing Community Level Action for Improved Maternal and Child Health and PMTCT (Project ACCLAIM).

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The Association between HIV Status and Antenatal Care Attendance among Pregnant Women in Rural Hospitals in Lesotho

Journal Articles

Early and frequent antenatal clinic (ANC) attendance is important for promotion of healthy outcomes for mother and child. This study explored the relationship between HIV status at the first ANC visit and subsequent ANC attendance among pregnant women in Lesotho.

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HIV-Positive Pregnant & Postpartum Women’s Perspectives about Option B

Journal Articles

The implementation of lifelong antiretroviral treatment (ART) for all pregnant women (Option B

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Challenges in the Elimination of Pediatric HIV-1 Infection

Journal Articles

By Katherine Luzuriaga, M.D., and Lynne M. Mofenson, M.D.

Preventing mother-to-child transmission of HIV-1 requires a series of steps in the care of women and their infants during pregnancy, delivery, and the postpartum period. This review outlines the steps and summarizes progress in resource-limited countries and elsewhere.

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Evaluating the effectiveness of selected community-level interventions on key maternal, child health, and prevention of mother-to-child transmission of HIV outcomes in three countries (the ACCLAIM Project): a study protocol for a randomized controlled trial

Journal Articles

Efforts to scale up and improve programs for prevention of mother-to-child transmission of HIV (PMTCT) have focused primarily at the health facility level, and limited attention has been paid to defining an effective set of community interventions to improve demand and uptake of services and retention. Many barriers to PMTCT are also barriers to pregnancy, childbirth, and postnatal care faced by mothers regardless of HIV status. Demand for maternal and child health (MCH) and PMTCT services can be limited by critical social, cultural, and structural barriers. Yet, rigorous evaluation has shown limited evidence of effectiveness of multilevel community-wide interventions aimed at improving MCH and HIV outcomes for pregnant women living with HIV. We propose to assess the effect of a package of multilevel community interventions: a social learning and action component, community dialogues, and peer-led discussion groups, on the demand for, uptake of, and retention of HIV positive pregnant/postpartum women in MCH/PMTCT services.

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Pregnant and Postpartum Women’s Experiences and Perspectives on the Acceptability and Feasibility of Copackaged Medicine for Antenatal Care and PMTCT in Lesotho

Journal Articles

By Gill, Hoffman,Tiam, Mohai, Mokone, Isavwa, Mohale, Makhohlisa, Ankrah, Luo, Guay

To improve PMTCT and antenatal care-related service delivery, a pack with centrally prepackaged medicine was rolled out to all pregnant women in Lesotho in 2011. This study assessed acceptability and feasibility of this copackaging mechanism for drug delivery among pregnant and postpartum women.

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Lesotho's Minimum PMTCT Package: lessons learned for combating vertical HIV transmission using co-packaged medicines

Journal Articles

By Lotus McDougal, Mpolai M Moteetee, Florence Mohai, Malisebo Mphale, Binod Mahanty, Blandinah Motaung, Victor Ankrah

This article features our analysis of a program to improve prevention of mother-to-child HIV transmission (PMTCT) adherence by implementing a package given to all pregnant women (some including only prenatal vitamins and other information - some including both prenatal and PMTCT drugs for women who tested HIV-positive during pregnancy). This program was rolled out in Lesotho. Our study examines feasibility of the package.

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Maternal, Newborn, and Child Health: The Foundation of a Successful Response to Pediatric HIV

Fact Sheets

This fact sheet illustrates the importance of maternal, newborn and child health care in the context of HIV prevention, care and treatment. It also highlights EGPAF’s work within this field and how we have utilized the platform of maternal, newborn and child health programs to ensure HIV prevention, care and treatment access to many women, children and families.

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