Journal Articles

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Introduction of Syphilis Point-of-Care Tests, from Pilot Study to National Programme Implementation in Zambia: A Qualitative Study of Healthcare Workers' Perspectives on Testing, Training and Quality Assurance

By Ansbro ÉM, Gill MM, Reynolds J, et al. PloS One. June 2015

This study examined the feasibility of scaling up rapid syphilis testing in Zambia. The study assessed health worker perspectives and health facility responses in facilities piloting point-of-care technology to provide rapid syphilis diagnostics.

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Scaling up pediatric HIV care and treatment in Africa: clinical site characteristics associated with favorable service utilization

By Adjorlolo-Johnson G1, Wahl Uheling A, Ramachandran S. et al. J Acquir Immune Defic Syndr. January 2013

To improve pediatric enrollment and retention in HIV treatment programs in Africa, this study examined factors associated with service utilization within EGPAF programs in Côte d'Ivoire, Mozambique, South Africa, Tanzania and Zambia.

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A multi-disciplinary approach to implementation science: the NIH-PEPFAR PMTCT implementation science alliance

By Sturke R, Harmston C, Simonds RJ, et al. J Acquir Immune Defic Syndr. November 2014.

In resource-limited countries, interventions to prevent mother-to-child HIV transmission have not yet realized their full potential health impact, illustrating the common gap between the scientific proof of an intervention's efficacy and effectiveness and its successful implementation at scale into routine health services.  

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Temporal trends in treatment outcomes for HIV-1 and HIV-2-infected adults enrolled in Côte d’Ivoire

By Auld AF, Ekra KA, Shiraishi RW, et al. PloSOne May 2014.

This study conducted a retrospective chart review to assess trends in patient characteristics and attrition (death or loss to follow-up) over time, among a nationally representative sample of 3,682 adults (≥15 years) initiating antiretroviral therapy during 2004-2007 at 34 health facilities.

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Community-based approaches for prevention of mother to child transmission in resource-poor settings: a social ecological review

By Busza J, Walker D, Hairston A, et al. J Int AIDS Soc. July 2012.

This paper reviews community-based approaches that have been used in resource-limited settings to increase rates of prevention of mother-to-child HIV transmission service enrollment, retention in care and successful treatment outcomes. It aims to identify which interventions work, why they work and what knowledge gaps remain.

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Tuberculosis in human immunodeficiency virus-infected children starting antiretroviral therapy in Cote d’Ivoire

By Auld AF, Tuho MZ, Ekra KA, et al. Int J Tuberc Lung Dis. April 2014.

The objective of this study is to estimate tuberculosis incidence and determinants among ART enrollees.  

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Temporal Trends in Mortality and Loss to Follow-up Among Children Enrolled in Côte d’Ivoire’s National Antiretroviral Therapy Program

By Auld AF, Tuho MZ, Ekra KA, et al. Pediatr Infect Dis J. November 2014.

During 2004-2008, >2000 children (<15 years old) initiated antiretroviral therapy (ART) in Côte d'Ivoire. Nationally representative outcomes, temporal trends in outcomes during 2004-2008 and site-level outcome determinants have not been investigated.

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What will it take to eliminate pediatric HIV? Reaching WHO target rates of mother-to-child HIV transmission in Zimbabwe: a model-based analysis

By Ciaranello A, Perez F, Keatinge J, et al. PLoS Med. January 2012.

This study investigated uptake of prevention of mother-to-child HIV transmission services, infant feeding recommendations, and specific drug regimens necessary to achieve elimination of mother-to-child transmission of HIV in Zimbabwe.  

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Pregnancy outcomes and birth defects from an antiretroviral drug safety registry for women in South Africa and Zambia

By Liu KC, Farahani M, Mashamba T, et al. AIDS September 2014.

This study evaluates the safety of combination antiretroviral therapy in conception and pregnancy in different health systems.

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Lessons learned from early implementation of B+: The Elizabeth Glaser Pediatric AIDS Foundation experience

By Kieffer MP, Mattingly M, Giphart A, et al. J Acquir Immune Defic Syndr. 2014

This implementation science study analyzed data from 11 African countries supported by EGPAF to describe early experience implementing Option B+.

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