Journal Articles

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Barriers, facilitators and recommendations for the early infant diagnosis and treatment (EIDT) cascade: A qualitative study in Malawi

By E A Bobrow; A G Yemaneberhan, 2; M Phiri; L Katirayi; A Ahimbisibwe F Chimbwandira; N Buono

To understand barriers, facilitators and recommendations for five key steps in the early infant diagnosis and treatment (EIDT) cascade: (1) identification of HEIs; (2) infant testing; (3) sample processing and transport; (4) reporting results to mothers; (5) ART initiation for HEI.

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The Association between HIV Status and Antenatal Care Attendance among Pregnant Women in Rural Hospitals in Lesotho

Early and frequent antenatal clinic (ANC) attendance is important for promotion of healthy outcomes for mother and child. This study explored the relationship between HIV status at the first ANC visit and subsequent ANC attendance among pregnant women in Lesotho.

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HIV-positive pregnant and postpartum women's perspectives about Option B+ in Malawi: a qualitative study

By Katirayi, Namadingo, Phiri, Bobrow, Ahimbisibwe, Berhan, Buono, Moland, Tylleskär

The implementation of lifelong antiretroviral treatment (ART) for all pregnant women (Option B


Evaluation of a male engagement intervention to transform gender norms and improve family planning and HIV service uptake in Kabale, Uganda

By Elena Ghanotakisa, Theresa Hokeb, Rose Wilcherb, Samuel Fieldb, Sarah Mercerb, Emily A. Bobrowa, Mary Namubiruc, Leila Katirayi

Men’s limited understanding of family planning (FP) and harmful cultural gender norms pose obstacles to women’s FP use. Thirty-two model men called ‘Emanzis’ were recruited from the community in Kabale, Uganda to lead men from their peer group through a 10-session curriculum designed to transform gender norms and motivate men to engage in FP and HIV services.

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Challenges in the Elimination of Pediatric HIV-1 Infection

By Katherine Luzuriaga, M.D., and Lynne M. Mofenson, M.D.

Preventing mother-to-child transmission of HIV-1 requires a series of steps in the care of women and their infants during pregnancy, delivery, and the postpartum period. This review outlines the steps and summarizes progress in resource-limited countries and elsewhere.

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Evaluating the effectiveness of selected community-level interventions on key maternal, child health, and prevention of mother-to-child transmission of HIV outcomes in three countries (the ACCLAIM Project): a study protocol for a randomized controlled trial

Efforts to scale up and improve programs for prevention of mother-to-child transmission of HIV (PMTCT) have focused primarily at the health facility level, and limited attention has been paid to defining an effective set of community interventions to improve demand and uptake of services and retention. Many barriers to PMTCT are also barriers to pregnancy, childbirth, and postnatal care faced by mothers regardless of HIV status. Demand for maternal and child health (MCH) and PMTCT services can be limited by critical social, cultural, and structural barriers. Yet, rigorous evaluation has shown limited evidence of effectiveness of multilevel community-wide interventions aimed at improving MCH and HIV outcomes for pregnant women living with HIV. We propose to assess the effect of a package of multilevel community interventions: a social learning and action component, community dialogues, and peer-led discussion groups, on the demand for, uptake of, and retention of HIV positive pregnant/postpartum women in MCH/PMTCT services.

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Pregnant and Postpartum Women’s Experiences and Perspectives on the Acceptability and Feasibility of Copackaged Medicine for Antenatal Care and PMTCT in Lesotho

By Gill, Hoffman,Tiam, Mohai, Mokone, Isavwa, Mohale, Makhohlisa, Ankrah, Luo, Guay

To improve PMTCT and antenatal care-related service delivery, a pack with centrally prepackaged medicine was rolled out to all pregnant women in Lesotho in 2011. This study assessed acceptability and feasibility of this copackaging mechanism for drug delivery among pregnant and postpartum women.

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Lesotho's Minimum PMTCT Package: lessons learned for combating vertical HIV transmission using co-packaged medicines

By Lotus McDougal, Mpolai M Moteetee, Florence Mohai, Malisebo Mphale, Binod Mahanty, Blandinah Motaung, Victor Ankrah

This article features our analysis of a program to improve prevention of mother-to-child HIV transmission (PMTCT) adherence by implementing a package given to all pregnant women (some including only prenatal vitamins and other information - some including both prenatal and PMTCT drugs for women who tested HIV-positive during pregnancy). This program was rolled out in Lesotho. Our study examines feasibility of the package.

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Implementation of Point-of-Care Diagnostics Leads to Variable Uptake of Syphilis, Anemia and CD4+ T-Cell Count Testing in Rural Maternal and Child Health Clinics

By De Schacht, Lucas, Sitoe, Machekano, Chongo, Temmerman, Tobaiwa, Guay, Kassaye, Jani. August 2015

This manuscript features EGPAF's work in scaling up point of care technology to address both the HIV and syphilis epidemics in maternal, newborn and child health settings in Mozambique.

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Scaling Down to Scale Up: A Health Economic Analysis of Integrating Point-of-Care Syphilis Testing into Antenatal Care in Zambia during Pilot and National Rollout Implementation

By Shelley KD, Ansbro ÉM, Ncube AT, Sweeney S, Fleischer C, Mumba GT, Gill MM, Strasser S, Peeling RW, Terris-Prestholt F. May 2015

An analysis of cost implications of implementation of a national plan to scale-up rapid syphilis testing in health sites across Zambia.

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