Clinical effect and cost-effectiveness of incorporation of point-of-care assays into early infant HIV diagnosis programmes in Zimbabwe
Simone C. Frank, Jennifer Cohn, Lorna Dunning et al. Manuscript in the LANCET HIV
Pediatric HIV Diagnosis, Care and Treatment; POC EID; Point-of-Care Early Infant Diagnosis; Strategic Information, Evaluation and Research
Using the Cost Effectiveness of Preventing AIDS Complications (CEPAC)—Pediatric model, the study team examined the clinical benefits, costs, and cost-effectiveness of replacing conventional assays for early infant HIV diagnosis with point-of-care (POC) assays at age 6 weeks in Zimbabwe. Compared with conventional assays, POC assays for early infant HIV diagnosis in Zimbabwe were found to improve survival, extend life expectancy of HIV-exposed infants. They are also more cost-effective than conventional assays.