Journal Articles | February 2019

Clinical effect and cost-effectiveness of incorporation of point-of-care assays into early infant HIV diagnosis programmes in Zimbabwe

A modelling study
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Overview

Created by:

Simone C. Frank, Jennifer Cohn, Lorna Dunning et al. Manuscript in the LANCET HIV

Country:

Zimbabwe

Topics:

Pediatric HIV Diagnosis, Care and Treatment; POC EID; Point-of-Care Early Infant Diagnosis; Strategic Information, Evaluation and Research

Using the Cost Effectiveness of Preventing AIDS Complications (CEPAC)—Pediatric model, the study team examined the clinical benefits, costs, and cost-effectiveness of replacing conventional assays for early infant HIV diagnosis with point-of-care (POC) assays at age 6 weeks in Zimbabwe. Compared with conventional assays, POC assays for early infant HIV diagnosis in Zimbabwe were found to improve survival, extend life expectancy of HIV-exposed infants. They are also more cost-effective than conventional assays.