Foot notes:

  1. Turnaround time for results to caregiver for conventional EID consists of a range of median number of days between blood sample drawn to receipt of results to caregiver, extracted from the literature. 
  2. As of July 21, 2017, prospective data is available for Cameroon, Cote D’Ivoire, Lesotho, Mozambique, Rwanda, Swaziland and Zimbabwe.
  3. Hub and Spoke model vs. Stand-alone testing sites: A “stand alone” testing site processes EID collected at their own facilities. A “hub and spoke” model places POC platforms in a high-volume, centrally located facility “hub” with smaller health outposts “spokes” delivering samples for faster diagnoses to these hubs (thereby supporting/alleviating national laboratories of EID samples to process). In both stand-alone and hub testing sites, the project will increase the number of HIV-positive infants identified by making EID testing available not only in PMTCT delivery sites, but also in pediatric inpatient wards, nutrition centers and immunization clinics.

References:

*On the Fast-Track to an AIDS-Free Generation, UNAIDS, 2016.

**Jani I, Meggi B, Vubil A, Sitoe NE, Bhatt N, Tobaiwa O, Quevedo JI, Loquiha O, Lehe JD, Vojnov L, Peter TF. (2016). Evaluation of the whole-blood Alere Q NAT point-of-care RNA assay for HIV-1 viral load monitoring in a primary health care setting in Mozambique. J Clin Microbiol 54:2104–2108

**Manumbu S, Smart LR, Mwale A, Mate KS, Downs JA. (2015). Shortening Turnaround Times for Newborn HIV Testing in Rural Tanzania: A Report from the Field. PLoS Med. Nov; 12(11).

** Mugambi ML, Deo S, Kekitiinwa A, Kiwaga C, Singer ME. (2013). Do diagnosis delays impact receipt of test results? Evidence from the HIV early infant diagnosis program in Uganda. PLoS ONE; 8.

**Phiri NA, Lee H-Y, Chilenga L, Mtika C, Sinyiza F, Musopole O, Nyirenda R, Yu J K-L, Harris AD. (2017). Early infant diagnosis and outcomes in HIV-exposed infants at a central and a district hospital, Northern Malawi. Public Health Action. Jun 21; 7(2): 83–89

**Sutcliffe CG, van Dijk JH, Hamangaba F, Mayani F, Moss WJ. (2014). Turnaround time for early infant diagnosis in rural Zambia: A chart review. PLoS ONE. 9(1)