Infant and Young Child Feeding

Protocol Title: Pilot test of HIV and Infant Feeding Indicator in Lesotho

About this study: This was a cross-sectional pilot study, funded by the World Health Organization, that analyzed data (August-December 2012) in six children’s clinics in Lesotho. Specifically, this study compared health care worker routinely collected information around infant feeding and ARV use in HIV-exposed infants to practices recorded in interviews with the clients themselves (administered by study staff). The objective was to determine whether the data recorded in clinic registers using the new indicators reflected actual feeding practices and ARV uptake among HIV-exposed infants.

Status: This study has been completed.

Resources Published to Date:

Protocol Title: The Kabeho Study: Kigali Antiretroviral and Breastfeeding Assessment for the Elimination of HIV (*Kabeho – is a Kinyarwanda word for wishing someone a long life)

About this study: In April 2012, the Government of Rwanda implemented a policy that would allow all HIV-positive women to be initiated on lifelong antiretroviral treatment (ART), known as Option B+. Rwanda also instituted an innovative infant feeding counseling and support program for HIV-positive women in the prevention of mother-to-child HIV transmission (PMTCT) programs.

This study, known as Kabeho, takes advantage of a unique opportunity to both evaluate maternal and child outcomes in Rwanda Option B+ program.  The primary objective of this four-year study is to determine the 24-month HIV-free survival in a cohort of children born to approximately 600 HIV-positive pregnant women in 14 high volume antenatal clinics in Kigali, Rwanda, that are participating in the Rwanda National PMTCT program. Additional objectives include determining the individual- and facility-level factors associated with: 1) healthy infant nutritional outcomes (as defined by lack of stunting, underweight, or wasting) in the cohort of HIV-exposed children and 2) adherence to the Option B+ ART regimen among pregnant/postpartum women and their HIV-exposed children; and to document birth outcomes in the cohort of study infants exposed to triple drug ART regimens in utero.

The study utilizes a prospective observational cohort design and collects individual and facility data through a mixed methods approach with both quantitative and qualitative data. In addition, interviews with health care providers and PMTCT program leaders are conducted to assess implementation successes and challenges, and to gather recommendations for program improvement.

Status: This study is ongoing.

View more information and resources on the Kabeho Study.